AbstractObjective To investigate risks of recurrence of cerebral palsy in family members with various degrees of relatedness to elucidate patterns of hereditability.Setting Data from the Medical Birth Registry of Norway, linked to the Norwegian social insurance scheme to identify cases of cerebral palsy and to databases of Statistics Norway to identify relatives.Participants 2036741 Norwegians born during 1967 2002, 3649 of whom had a diagnosis of cerebral palsy; 22558 pairs of twins pandora rings, 1851144 pairs of first degree relatives, 1699856 pairs of second degree relatives, and 5165968 pairs of third degree relatives were identified.Main outcome measure Cerebral palsy.Results If one twin had cerebral palsy https://www.charmspandora-canada.com/, the relative risk of recurrence of cerebral palsy was 15.6 (95% confidence interval 9.8 to 25) in the other twin. In families with an affected singleton child, risk was increased 9.2 (6.4 to 13) fold in a subsequent full sibling and 3.0 (1.1 to 8.6) fold in a half sibling. Affected parents were also at increased risk of having an affected child (6.5 (1.6 to 26) fold).
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